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New system speeds screening of drug-delivering nanoparticles
A new study demonstrates ‘species agnostic’ screening of lipid nanoparticles, which could significantly accelerate the development of cutting edge mRNA targeted therapies. Long before the Covid-19 pandemic put a global spotlight on mRNA-based vaccines, these two researchers in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University were combining their…
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Scientists develop sensor to save children, pets left in vehicles
A small, inexpensive sensor could save lives by triggering an alarm when children or pets are left alone in vehicles. The new device combines radar technology with artificial intelligence (AI) to detect unattended children or animals with 100-per-cent accuracy. The new device, developed by researchers at the University of Waterloo, combines radar technology with artificial…
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Smart insole can double as lifesaving technology for diabetic patients
Researchers are developing a graphene sensing system that detects early signs of foot ulcers before they form so people living with diabetes can access preventative healthcare and confidently manage their health. The smart insole, Bonbouton’s first product, can be inserted into a sneaker or dress shoe to passively monitor the foot health of a person…
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New atomistic level insight into drug-target residence time
A new study helps to explain what defines how long a drug molecule stays bound to its target. When a drug molecule binds to its target protein, it stays bound for some time before eventually unbinding the target. The actual time how long a drug molecule resides bound to its target varies among compounds. The…
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Photoinitiators detected in human breast milk
Photoinitators (PIs) are compounds used in the ink of many types of food packaging. The substances have been shown to migrate into food and, when consumed, show up in human blood serum. Now, for the first time, researchers report they have detected PIs in human breast milk, although they say the levels consumed by breastfeeding…
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On the dot: Novel quantum sensor provides new approach to early diagnosis via imaging
A phenomenon called ‘oxidative stress’ is seen in affected organs during the early stages of certain difficult-to-treat diseases like cancer and kidney dysfunction. Detecting oxidative stress could thus enable early diagnosis and preventive treatments. But, the in vivo measurement of oxidative stress caused by both oxidation and reduction has historically been difficult. Now, scientists have…
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New promising treatment uses smart nanoparticles to target lung cancer
A new and promising approach for treatment of lung cancer has been developed. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. Lung tumors are often difficult to remove using current surgical techniques due to their location in the lung or the fact that there are multiple tumors which…
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Scientists develop tougher, safer bicycle helmets using new plastic material
Researchers have developed a tougher, safer bicycle helmet using a combination of materials. The new helmet prototype has higher energy absorption, reducing the amount of energy transferred to a cyclist’s head in the event of an accident and likely lowering the chances of serious injury. According to a World Health Organisation report in 2020, more…
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Microfilter device capable of detecting trace amounts of cancer cells in one mL of blood
Researchers have developed a microfilter device that can easily separate and capture trace amounts of cancer cells in blood. The palm-sized device is expected to contribute to the development of new cancer diagnostic technologies based on cancer cells in the blood, such as early detection by blood test, postoperative management, and recurrence monitoring. The blood…
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Brightest ever X-ray shows lung vessels altered by COVID-19
The damage caused by COVID-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists from UCL and the European Synchrotron Research Facility (ESRF) used a new revolutionary imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from…