In a new article, scientists explain how tears ejected from the eye during a procedure that tests for glaucoma can theoretically transmit disease. In Physics of Fluids, by AIP Publishing, scientists from the Indian Institute of Science and the Narayana Nethralaya Foundation explain how tears ejected from the eye during a procedure that tests for…

A new imaging technique can measure temperature in 2D, without contact, and in just a snap. This technology, known as single-shot photoluminescence lifetime imaging thermometry (SPLIT), is based on the luminescence of nanoparticles doped with rare earth ions. «They are considered as nanothermometers because their luminescent properties change with the temperature of the environment. They…

Researchers have developed a powerful miniature brain platform to study the mechanistic causes of Alzheimer’s disease and to test dementia drugs in development. «Drug development for Alzheimer’s disease has run into challenges due to incomplete understanding of the disease’s pathological mechanisms,» said Yanhong Shi, Ph.D., the Herbert Horvitz Professor in Neuroscience and director of the…

Proteins drive nearly all biological functions and insight into their workings is essential for pharmaceutical developments. But now, a pair of scientists from Japan have found that our fundamental understanding of a characteristic of proteins that is key to their proper functioning — the mechanism by which their structures fold — has been flawed. These…

Scientists have obtained the first high-resolution 3D image of nebulin, a giant actin-binding protein that is an essential component of skeletal muscle. This discovery has brought to light the chance to better understand the role of nebulin, as its functions have remained largely nebulous due to its large size and the difficulty in extracting nebulin…

Highly efficient (electro-)catalysts are essential for the production of green hydrogen, the chemical industry, fertilizer production and other sectors of the economy. In addition to transition metals, a variety of other metallic or non-metallic elements have now moved into the focus of research. In addition to transition metals, which are already well studied for their…

By using 3D aerosol jet-printing to put perovskites on graphene, scientists have made X-ray detectors with record sensitivity that can greatly improve the efficiency and reduce the cost and health hazard of medical imaging devices. There has been a lot of progress since. Aside from radiographs, which most people have taken at least once in…

Glass windows typically offer some amount of sound proofing, sometimes unintentionally. In general, ventilation is required to achieve large sound transmission. But some applications — like gas explosion studies — require a transparent partition that allows for acoustic propagation without the presence of airflow. In those cases, ventilation is not allowed. Researchers discuss a layered…

Researchers have developed a CRISPR-based assay that can sensitively and non-invasively detect a biomarker of acute kidney rejection in urine. This could someday help diagnose rejection earlier and without a biopsy. Kidney transplant recipients must take immunosuppressant drugs for the rest of their lives to help keep their immune systems from attacking the foreign organ.…

Drug addiction is a vicious cycle of reward and withdrawal. Chronic users often relapse because of the unpleasant physical and psychological symptoms they experience when they stop taking the drug. Now, researchers report metabolic changes in the brains of rats during methamphetamine self-administration and withdrawal that could help identify biomarkers and treatments for addiction. Methamphetamine…