Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways. These are the conclusions from a stud investigating a large number of cell samples from patients with brain tumors. The researchers have characterized how changes in glioblastoma cells influence the effect of different drugs.…

Researchers have found that low-intensity exercise, which is associated with improved mental function, has a protective effect against symptoms of schizophrenia in adolescent mice. These findings may facilitate the development of exercise programs to help prevent schizophrenia in humans. In a study published this month in Biochemical and Biophysical Research Communications, researchers from the University…

The national Ocular Hypertension Treatment Study was designed to determine whether lowering elevated eye pressure in patients might prevent vision loss from glaucoma. Researchers recently completed follow-up studies on patients 20 years after the start of the original study and found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision…

Restoring hearing through cochlear implantation for children with autism spectrum disorder (ASD) can help them understand spoken language and enhance social interactions, according to a new study. «Our results add to the growing body of evidence that cochlear implantation clearly benefits deaf children with autism spectrum disorder,» said senior author Nancy Young, MD, Medical Director…

Researchers have identified how specific brain cells interacting during development could be related to neurological and neuropsychiatric diseases, including some that occur later in life. Brain function depends on the precise formation of millions of connections between specific brain cell types, including neurons and glial cells. The scientists at CU studied how a type of…

Borderline Personality Disorder is treatable. New research is the first to show that adolescent borderline pathology follows a similar downward course after discharge from inpatient treatment previously demonstrated for adults. And her new research, published in Journal of Abnormal Child Psychology backs her up. «Like adult BPD, adolescent BPD appears to be not as intractable…

Inside cells, organelles called mitochondria carry out a medley of vital tasks. These structures generate energy and help to keep the cells’ interior environment in a state of healthy equilibrium, among other functions. Now, scientists show in detail how alpha-synuclein, a protein associated with Parkinson’s disease, can damage these cellular powerhouses. Now, scientists show how…

Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents’ lives. The scientists used antisense oligonucleotides (ASOs), synthetic compounds that inhibit the formation of specific proteins. Prion diseases occur when normally harmless prion protein molecules become abnormal and…

People living with obesity who attended a non-judgemental and personalized lifestyle modification program improved their cardiovascular and mental health during just 10 weeks, according to a new study. Participants lost weight and achieved benefits in anxiety and depression and physical measurements including blood pressure. «We focus on changing behaviours and improving people’s relationship with food,»…

A new article describes the approach, structure, and launch of the HEALEY ALS Platform Trial- the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness. «This study is really the first comprehensive platform for ALS drug development, where a central infrastructure…