A new cloud-based data resource provides the research community with a comprehensive set of tools to help identify new subtypes of amyotrophic lateral sclerosis (ALS), a fatal neurological disorder. The web-based tool is part of a collaborative effort with more than 100 scientists called Answer ALS, which includes biological and clinical data from more than…

Young adults who develop PTSD after a traumatic event (e.g., gun violence, sexual assault, military combat or natural disaster) may be more likely to experience a transient ischemic attack (TIA) or major stroke event by middle age. This nationwide study of more than 1.1 million adults showed that PTSD may be a potent risk factor…

In sudden death in epilepsy, people stop breathing for no apparent reason and die. Now, a group of UConn neuroscientists have a lead as to why. Many neurologists argue that a bad seizure can travel through the brain to cause breathing or heartbeat malfunction, and that’s what kills. But epileptics can die suddenly without having…

A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection—including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs. Currently, most HIV therapies for treatment and prevention (pre-exposure prophylaxis, PrEP) necessitate…

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to schizophrenia using neurons derived from induced pluripotent stem cells. Co-ordinated by the University…

A study is the first to examine the relationship between parental mental illness like anxiety and depression in childhood and the risk of suicide and self-harm in adults who suffer from tinnitus, noise or ringing in the ears, and hyperacusis, extreme sensitivity to noise. Results show that among patients seeking help for these debilitating hearing…

Korean research team made up of Dr. Hyung-Jun Kim and Shinrye Lee of KBRI, and professor Kiyoung Kim of Soonchunhyang University, found a new molecular mechanism of suppressing neuronal toxicity associateded dementia and Lou Gehrig’s disease. These findings were published in the November issue of Autophagy Neurons in patients with dementia or Lou Gehrig’s disease…

Neuroblastoma is a type of childhood cancer that develops in infants and young children. Whilst it is a relatively rare form of cancer, it is still responsible for approximately 15 percent of all cancer deaths in children. Researchers have discovered that low-risk and high-risk neuroblastoma have different cell identities, which can affect the survival rate.…

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need. The drug, cabozantinib, is a tyrosine kinase inhibitor that attacks several targets in cancer cells.…

Researchers have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease. The discovery, published in the peer-reviewed journal Nature Communications, can also help lead to a new treatment approach for people suffering from the disease. Cases of alcohol-associated liver disease…