-
Important questions on how mental illness is currently diagnosed
This research raises questions as to whether current diagnoses accurately reflect the underlying neurobiology of mental illness. The findings, just published in the leading peer-reviewed medical journal, JAMA Psychiatry, highlight the need for more individualised approaches to defining mental illness. The findings, just published in the leading peer-reviewed medical journal, JAMA Psychiatry, are significant in…
-
COVID-19 infection may be part of a ‘perfect storm’ for Parkinson’s disease
Can COVID-19 infection increase the risk of developing Parkinson’s disease? That’s the question posed by a new commentary that explores three known case studies of people developing Parkinson’s-like symptoms in the weeks following infection with SARS-CoV-2. That’s the question posed by a new commentary published in the journal Trends in Neurosciences, which explores three known…
-
Burst of radiation and vesicles-based immunotherapy suppress brain cancer growth
The priming of glioblastoma with a burst of radiation increased dramatically the uptake of extracellular vesicles-based immunotherapy by the tumor and the surrounding microenvironment, halting tumor growth, inducing anti-tumor immunity, and prolonging survival in animal models. In glioblastomas primed with radiation, extracellular vesicles allowed the immunotherapy to cross the blood-brain barrier, recruiting immune cells to…
-
Thyroid screening may not be needed in all youth with psychiatric disorders
A new study looks at the prevalence of abnormal thyroid function in youth with severe mood and anxiety disorder. It is the largest study to date of this population and will help mental health professionals better understand the predictors of abnormal thyroid function, like weight gain, family history, or treatment with specific medications. «I was…
-
Targeting a rare secondary cancer in children
Known as pediatric radiation-induced high-grade gliomas (RIGs), this specific type of brain tumor is caused by cranial radiation therapy for other cancers, most often brain cancers. They account for nearly 4% of all childhood brain tumor deaths, but there have not been many studies on RIGs and how to treat them. «It’s especially tragic because…
-
Could excessive sugar intake contribute to aggressive behaviors, ADHD, bipolar disorder?
New research suggests that conditions such as attention deficit hyperactivity syndrome (ADHD), bipolar disorder, and even aggressive behaviors may be linked with sugar intake, and that it may have an evolutionary basis. The research, out today from the University of Colorado Anschutz Medical Campus and published in Evolution and Human Behavior, presents a hypothesis supporting…
-
Yearlong birth control supply would cut unintended pregnancies, costs
By dispensing a year’s worth of birth control pills up front, the VA could prevent 583 unintended pregnancies and save $2 million per year on health care costs each year. The paper, published today in JAMA Internal Medicine, used a mathematical model to demonstrate that reducing birth control refills would better allow female veterans to…
-
World’s first congenital pituitary hypoplasia model developed using patient-derived iPS cells
Researchers have developed the world’s first congenital pituitary hypoplasia (CPH) model using patient-derived iPS cells. The research group succeeded in using the model to illuminate the mechanisms underlying CPH. The team has been attempting to apply this model to other pituitary diseases and drug discovery. The results of this study were published in the American…
-
Does pregnancy history affect cognitive function?
Healthy cognitive aging is a public health priority, especially as the US population grows older. Until now, not much has been known about the link between pregnancy history and cognitive function in older women. A new study finds that there does not appear to be a link. There are a number of reproductive and pregnancy…