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Novel assessment of platelet-rich plasma treatment shows efficacy in patients with osteoarthritis
A pilot study combined wearable technology and patient-reported outcomes to assess the efficacy of platelet-rich plasma (PRP) treatment in osteoarthritis (OA), finding significant improvements. The results, published in the journal Regenerative Medicine, showed that a single injection of leukocyte-rich/PRP in the knee joint significantly improved functional mobility, pain and quality of life after six weeks.…
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Ongoing ‘immune injuries’ might cause persistent breathlessness after COVID-19
Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19, according to new research. This is according to a new study of 38 people who were previously hospitalised with severe COVID-19. The results, published in Immunity, suggest these patients have an altered landscape of immune cells in their airways and…
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Machine learning tool detects the risk of genetic syndromes in children with diverse backgrounds
With an average accuracy of 88%, a deep learning technology offers rapid genetic screening that could accelerate the diagnosis of genetic syndromes, recommending further investigation or referral to a specialist in seconds, according to a new study. Trained with data from 2,800 pediatric patients from 28 countries, the technology also considers the face variability related…
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Ultrasound blasts potent glioblastoma drug into brain tumor
A potent drug for glioblastoma can’t be used in patients. It can’t reach its target because it’s blocked by the blood-brain barrier, and the conventional formulation for this drug is toxic to the brain. But now scientists have used a novel technology for opening the blood-brain barrier with an implantable ultrasound, and delivered the powerful…
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Hundreds of antibiotic resistant genes found in the gastrointestinal tracts of Danish infants
Danish one-year-olds carry several hundred antibiotic resistant genes in their bacterial gut flora according to a new study from the University of Copenhagen. The presence of these genes is partly attributable to antibiotic use among mothers during pregnancy. Danish one-year-olds carry several hundred antibiotic resistant genes in their bacterial gut flora according to a new…
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New technique could help regrow tissue lost to periodontal disease
About half of all Americans will have periodontal disease at some point in their lives. Characterized by inflamed gums and bone loss around teeth, the condition can cause bad breath, toothache, tender gums and, in severe cases, tooth loss. Now, researchers report development of a membrane that helps periodontal tissue regenerate when implanted into the…
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Protective mutations in COVID-19
One way in which the body combats COVID-19 is by mutating the coronavirus, making it less harmful. This built-in protective mechanism in cells has a clear connection with decreased viral load in the body, a new study shows. Mutations are often associated with the emergence of virus variants that are more contagious and pathogenic than…
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Drug eases recovery for those with severe alcohol withdrawal
Scientists say a drug originally developed to treat high blood pressure can reduce severe withdrawal symptoms for patients diagnosed with alcohol use disorder. In a double-blind study, researchers gave the drug prazosin or a placebo to 100 people entering outpatient treatment after being diagnosed with alcohol use disorder. All of the patients had experienced varying…
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A new therapeutic target turns the immune system against lymphoma
Scientists have identified a key mechanism that tumor cells use to take advantage of and avoid detection from the immune system. Targeting this mechanism offers a new therapeutic strategy for cancers like Non-Hodgkin lymphoma. Today, immunotherapy is one of the most promising treatment for cancer patients. Unlike radio- or chemo- therapies, immunotherapy aims to «switch…
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Study identifies exposure to common food-borne pathogen linked to rare brain cancer
A new study suggests a link between toxoplasma gondii (T. gondii) infection and the risk of glioma, a type of brain cancer, in adults. For the study, investigators led by James Hodge, JD, MPH and Anna Coghill, PhD examined the association between T. gondii antibodies measured several years before the cancer was diagnosed and the…