Researchers have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors. The modified «natural killer» cells can differentiate between cancer cells and healthy cells that are often intermingled in and around tumors, destroying only the targeted cells. The natural killer cells’ ability to…

Scientists have identified a new genetic mechanism that can cause severe forms of male infertility. This breakthrough in understanding the underlying cause of male infertility offers hope of better treatment options for patients in the future. This breakthrough in understanding the underlying cause of male infertility offers hope of better treatment options for patients in…

Multiple myeloma, the most common type of bone marrow cancer in Germany, almost always returns, even after initial treatment success. In the majority of cases, the reasons behind this treatment resistance (e.g., genetic mutations) and the subsequent return of the disease, remain unknown. According to new research, it is the increased production of a specific…

An artificial intelligence program accurately predicts the risk that lung nodules detected on screening CT will become cancerous, according to a new study. Lung cancer is the leading cause of cancer death worldwide, with an estimated 1.8 million deaths in 2020, according to the World Health Organization. Low-dose chest CT is used to screen people…

Researchers have created a biodegradable nerve guide — a polymer tube — filled with growth-promoting protein that can regenerate long sections of damaged nerves, without the need for transplanting stem cells or a donor nerve. So far, the technology has been tested in monkeys, and the results of those experiments appeared today in Science Translational…

Analyzing anonymized patient medical records, researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why. UC San Diego Health researchers recently reported that statins — widely used cholesterol-lowering medications — are associated with reduced risk of developing severe COVID-19 disease, as well as…

Researchers have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already known for effectively targeting HIV-1 envelope (Env) protein can prevent infected cells from releasing viral particles, thus halting viral spread. The findings demonstrate that these powerful antibodies exhibit different…

Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS-CoV-2 in the lungs. The findings will help inform future treatment options for the current pandemic and future coronaviruses. Researchers at Texas Biomedical Research Institute and Southwest National Primate Research Center (SNPRC), in collaboration with…

This experiment marks the first time researchers have ever successfully introduced mitochondria into specific cells in living animals. The study lays the groundwork to address a serious gap in treatment for liver diseases and may even eventually be used to treat other maladies throughout the body affected by mitochondrial malfunction or damage. This groundbreaking experiment…

Researchers have shown in mice models of Alzheimer’s disease, frontotemporal dementia, and dementia with Lewy bodies, that the intranasal administration of rifampicin and resveratrol in combination is safer and improves cognitive function more than rifampicin alone. The research results are expected to lead to the development of safe and effective nasal spray for the prevention…