New treatment for brain tumors uses electrospun fiber


Researchers have developed a new treatment for glioblastoma multiforme, an aggressive form of brain cancer.

University of Cincinnati professor Andrew Steckl, working with researchers from Johns Hopkins University, developed a new treatment for glioblastoma multiforme, or GBM, an aggressive form of brain cancer. Steckl’s Nanoelectronics Laboratory applied an industrial fabrication process called coaxial electrospinning to form drug-containing membranes.

The treatment is implanted directly into the part of the brain where the tumor is surgically removed.

The study was published in Nature Scientific Reports.

«Chemotherapy essentially is whole-body treatment. The treatment has to get through the blood-brain barrier, which means the whole-body dose you get must be much higher,» Steckl said. «This can be dangerous and have toxic side-effects.»

Steckl is an Ohio Eminent Scholar and professor of electrical engineering in UC’s College of Engineering and Applied Science.


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Materials provided by University of Cincinnati. Note: Content may be edited for style and length.


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