Dairy cows, exposed for a few years to drinking water contaminated with heavy metals, carry more pathogens loaded with antimicrobial-resistance genes able to tolerate and survive various antibiotics. That’s the finding of a team of researchers that conducted a study of two dairy herds in Brazil four years after a dam holding mining waste ruptured, and it spotlights a threat to human health, the researchers contend.

That’s the finding of a team of researchers that conducted a study of two dairy herds in Brazil four years after a dam holding mining waste ruptured, and it spotlights a threat to human health, the researchers contend.

The study is the first to show that long-term persistence of heavy metals in the environment may trigger genetic changes and interfere with the microorganism communities that colonize dairy cows, according to researcher Erika Ganda, assistant professor of food animal microbiomes, Penn State.

«Our findings are important because if bacterial antimicrobial resistance is transferred via the food chain by milk or meat consumption, it would have substantial implications for human health,» she said. «What we saw is, when heavy metal contamination is in the environment, there is potential for an increase of so-called ‘superbugs.’»

A declaration from the World Health Organization supports Ganda’s assertion, saying that resistance to antimicrobials is one of the top 10 global public health threats facing humanity. Antimicrobial resistance occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines, making infections harder to treat and increasing the risk of disease spread, severe illness and death.

A South American environmental calamity triggered the research. Known as the Mariana Dam disaster, in 2015 the Fundao Tailings Dam suffered a catastrophic failure and released more than 11 billion gallons of iron ore waste. The huge wave of toxic mud flowed into the Doce River basin surrounding Mariana City in Minas Gerais, a state in southeast Brazil.

Story Source:
Materials provided by Penn State. Original written by Jeff Mulhollem. Note: Content may be edited for style and length.